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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

ACCN4 Antibody

CATALOG NUMBER: 58-541

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ACCN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human ACCN4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
70 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ASIC4
Additional Names:
Acid-sensing ion channel 4, ASIC4, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, pituitary, ASIC4, ACCN4
Protein Accession Number:
Q96FT7
Protein Gi Number:
296434387
Ncbi Gene Id Number:
55515
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the superfamily of acid-sensing ionchannels, which are proton-gated, amiloride-sensitive sodiumchannels. These channels have been implicated in synaptictransmission, pain perception as well as mechanoperception. Thisgene is predominantly expressed in the pituitary gland, and wasconsidered a candidate for paroxysmal dystonic choreoathetosis(PDC), a movement disorder, however, no correlation was foundbetween mutations in this gene and PDC. Alternative splicing atthis locus results in two transcript variants encoding differentisoforms.
Background Reference 1:
Donier, E., et al. Eur. J. Neurosci. 28(1):74-86(2008)
Background Reference 2:
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Background Reference 3:
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Background Reference 4:
Grunder, S., et al. Eur. J. Hum. Genet. 9(9):672-676(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-541

List Size:
400 ul

List Price:

$495.00

Datasheet
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