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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

ACSL4 Antibody

CATALOG NUMBER: 57-712

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This ACSL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ACSL4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
79 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ACSL4
Additional Names:
Long-chain-fatty-acid--CoA ligase 4, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4
Protein Accession Number:
O60488
Ncbi Gene Id Number:
2182
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an isozyme of thelong-chain fatty-acid-coenzyme A ligase family. Although differingin substrate specificity, subcellular localization, and tissuedistribution, all isozymes of this family convert free long-chainfatty acids into fatty acyl-CoA esters, and thereby play a key rolein lipid biosynthesis and fatty acid degradation. This isozymepreferentially utilizes arachidonate as substrate. The absence ofthis enzyme may contribute to the mental retardation or Alportsyndrome. Alternative splicing of this gene generates 2 transcriptvariants.
Background Reference 1:
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Background Reference 2:
Zhang, Y., et al. Hum. Mol. Genet. 18(20):3894-3905(2009)
Background Reference 3:
Zeman, M., et al. Tohoku J. Exp. Med. 217(4):287-293(2009)
Background Reference 4:
An, C., et al. Neurosci. Lett. 441(2):197-200(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-712

List Size:
400 ul

List Price:

$495.00

Datasheet
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