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Activin A Recombinant Protein

CATALOG NUMBER: 40-213

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
Biological Activity:
The ED50 was determined by its ability to inhibit the proliferation of murine MPC - 11 cells is ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Purity:
Greater than 97% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized Activin A recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Activin A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Activin A recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
SMAD2
Additional Names:
JV18, MADH2, MADR2, JV18-1, hMAD-2, hSMAD2, Mothers against decapentaplegic homolog 2, MAD homolog 2
Protein Accession Number:
NP_001003652.1
Protein Gi Number:
51173730
Ncbi Gene Id Number:
4087
Background:
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-213

List Size:
0.002 mg, 0.01 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

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