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Activin Receptor IIB Antibody

CATALOG NUMBER: 36-351

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant extracellular domain (ecd) of mouse activin receptor IIB.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application.
Specificity:
Recognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd.
Purification:
Antigen affinity purified.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide.
Concentration:
500 ug/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
Acvr2b
Additional Names:
ACVR2B; ACTR-IIB; Activin receptor type-2B
Protein Accession Number:
114727
Protein Gi Number:
P27040
Ncbi Gene Id Number:
11481
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-351

List Size:
50 ug

List Price:

$658.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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