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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

ACTL7A Antibody

CATALOG NUMBER: 55-197

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ACTL7A
Additional Names:
Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
Protein Accession Number:
Q9Y615
Protein Gi Number:
27923725
Ncbi Gene Id Number:
10881
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ACTL7A is a member of a familyof actin-related proteins (ARPs) which share significant amino acidsequence identity to conventional actins. Both actins and ARPs havean actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, includingvesicular transport, spindle orientation, nuclear migration andchromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B,are intronless, and are located approximately 4 kb apart in ahead-to-head orientation within the familial dysautonomia candidateregion on 9q31. Based on mutational analysis of the ACTL7A gene inpatients with this disorder, it was concluded that it is unlikelyto be involved in the pathogenesis of dysautonomia. The ACTL7A geneis expressed in a wide variety of adult tissues, however, its exactfunction is not known.
Background Reference 1:
Aberg, K., et al. Hum. Biol. 80(2):99-123(2008)
Background Reference 2:
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Background Reference 3:
Garvalov, B.K., et al. J. Cell Biol. 161(1):33-39(2003)
Background Reference 4:
Coutts, A.S., et al. J. Cell. Sci. 116 (PT 5), 897-906 (2003) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-197

List Size:
400 ul

List Price:

$495.00

Datasheet
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