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E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

ADAM23 Antibody

CATALOG NUMBER: XW-7809

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
72-144
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
ADAM 23 antibody can be used for the detection of ADAM 23 by Western Blot.
Predicted Molecular Weight:
91.9 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
ADAM23 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ADAM23
Additional Names:
MDC3, Disintegrin and metalloproteinase domain-containing protein 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, ADAM 23, MDC3, MDC-3, A disintegrin and metalloproteinase domain 23
Protein Accession Number:
NP_003803.1
Protein Gi Number:
4501913
Ncbi Gene Id Number:
8745
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FUNCTION: May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

SUBUNIT: Ligand for integrin α-V/γ-3.

SIMILARITY: Contains 1 peptidase M12B domain.

SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein (Potential). Secreted protein. Isoform Gamma.

TISSUE SPECIFICITY: Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.

DEVELOPMENTAL STAGE: Highly expressed in the fetal brain.

DOMAIN:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.

SUMMARY: This protein is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is highly expressed in the brain and may function as an integrin ligand in the brain.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7809

List Size:
0.05 mg

List Price:

$638.00

Datasheet
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