Trial Size

ADAMTSL5 Antibody

CATALOG NUMBER: 5687

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
ADAMTSL5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ADAMTSL5.
The immunogen is located within the last 50 amino acids of ADAMTSL5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
ADAMTSL5 antibody can be used for detection of ADAMTSL5 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1375 - Human Skeletal Muscle Tissue Lysate
Purification:
ADAMTSL5 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgY
physical-state:
Liquid
Buffer:
ADAMTSL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
ADAMTSL5 antibody can be stored at 4°C, stable for up to one year. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ADAMTSL5
Additional Names:
ADAMTSL5 Antibody: THSD6, THSD6, ADAMTS-like protein 5, Thrombospondin type-1 domain-containing protein 6, ADAMTSL-5
Protein Accession Number:
NP_998769
Protein Gi Number:
226442878
Ncbi Gene Id Number:
339366
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ADAMTSL5 Antibody: ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
Background Reference 1:
Jones GC and Riley GP. ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis. Arth. Res. and Ther.2005; 7:160-9.
Background Reference 2:
Apte SS. A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms. J. Biol. Chem.2009; 284:31493-7.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5687

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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