ADORA1 Antibody

CATALOG NUMBER: 57-724

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ADORA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human ADORA1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ADORA1
Additional Names:
Adenosine receptor A1, ADORA1
Protein Accession Number:
P30542
Protein Gi Number:
231473
Ncbi Gene Id Number:
134
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is an adenosine receptorthat belongs to the G-protein coupled receptor 1 family. There are3 types of adenosine receptors, each with a specific pattern ofligand binding and tissue distribution, and together they regulatea diverse set of physiologic functions. The type A1 receptorsinhibit adenylyl cyclase, and play a role in the fertilizationprocess. Animal studies also suggest a role for A1 receptors inkidney function and ethanol intoxication. Transcript variants withalternative splicing in the 5' UTR have been found for this gene.
Background Reference 1:
Lane, J.R., et al. Biochem. Pharmacol. 80(8):1180-1189(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 3:
Wagner, A.K., et al. Epilepsy Res. 90(3):259-272(2010)
Background Reference 4:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-724

List Size:
400 ul

List Price:

$495.00

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