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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

AFF2 Antibody

CATALOG NUMBER: 59-677

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AFF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 886-912 amino acids from the Central region of human AFF2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
145 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AFF2
Additional Names:
AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, FMR2P, Protein FMR-2, Protein Ox19, AFF2, FMR2, OX19
Protein Accession Number:
P51816
Protein Gi Number:
116241242
Ncbi Gene Id Number:
2334
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a putative transcriptional activatorthat is a member of the AF4FMR2 gene family. This gene isassociated with the folate-sensitive fragile X E locus onchromosome X. A repeat polymorphism in the fragile X E locusresults in silencing of this gene causing Fragile X E syndrome.Fragile X E syndrome is a form of nonsyndromic X-linked mentalretardation. Alternate splicing results in multiple transcriptvariants.
Background Reference 1:
Bensaid, M., et al. Nucleic Acids Res. 37(4):1269-1279(2009)
Background Reference 2:
Brylawski, B.P., et al. Exp. Mol. Pathol. 82(2):190-196(2007)
Background Reference 3:
Sharma, D., et al. Genet. Epidemiol. 20(1):129-144(2001)
Background Reference 4:
Hillman, M.A., et al. J. Hum. Genet. 46(5):251-259(2001)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-677

List Size:
400 ul

List Price:

$495.00

Datasheet
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