AFP Antibody

CATALOG NUMBER: XW-7017

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
180-420
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
68.7 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
AFP antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AFP
Additional Names:
HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, FETA, HPAFP,
Protein Accession Number:
NP_001125.1
Protein Gi Number:
4501989
Ncbi Gene Id Number:
174
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
α-1-fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Background Reference 1:
Gabant, P., Forrester, L., Nichols, J., Van Reeth, T., De Mees, C., Pajack, B., Watt, A., Smitz, J., Alexandre, H., Szpirer, C., Szpirer, J. Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc. Nat. Acad. Sci. 99: 12865-12870, 2002.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7017

List Size:
0.05 mg

List Price:

$663.00

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