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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

AKR1D1 Antibody

CATALOG NUMBER: 58-637

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AKR1D1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the Central region of human AKR1D1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AKR1D1
Additional Names:
3-oxo-5-beta-steroid 4-dehydrogenase, Aldo-keto reductase family 1 member D1, Delta(4)-3-ketosteroid 5-beta-reductase, Delta(4)-3-oxosteroid 5-beta-reductase, AKR1D1, SRD5B1
Protein Accession Number:
P51857
Protein Gi Number:
1703007
Ncbi Gene Id Number:
6718
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The enzyme encoded by this gene is responsible for thecatalysis of the 5-beta-reduction of bile acid intermediates andsteroid hormones carrying a delta(4)-3-one structure. Deficiency ofthis enzyme may contribute to hepatic dysfunction. Three transcriptvariants encoding different isoforms have been found for this gene.Other variants may be present, but their full-length natures havenot been determined yet.
Background Reference 1:
Steen, N.E., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry (2010) In press :
Background Reference 2:
Drury, J.E., et al. J. Biol. Chem. 285(32):24529-24537(2010)
Background Reference 3:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 4:
Ueki, I., et al. J. Gastroenterol. Hepatol. 24(5):776-785(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-637

List Size:
400 ul

List Price:

$495.00

Datasheet
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