AKT2 Antibody

CATALOG NUMBER: XW-7021

Clonality:
Polyclonal
Tested Applications:
ELISA
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
108-124
Conjugate:
Unconjugated
Tested Applications:
ELISA
Application Note:
AKT2 antibody can be used for the detection of AKT2 by Western blot, ELISA, may also work for IHC and ICC.
Predicted Molecular Weight:
55.8 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
AKT2 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AKT2
Additional Names:
Protein kinase Akt-2, PKB beta, PKBB, PRKBB, HIHGHH, PKBBETA, RAC-BETA,
Protein Accession Number:
NP_001617.1
Protein Gi Number:
4502023
Ncbi Gene Id Number:
208
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Murine thymoma viral (v-akt) homolog-2; rac protein kinase β. AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Background Reference 1:
Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., Testa, J. R. Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Nat. Acad. Sci. 93: 3636-3641, 1996.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7021

List Size:
0.05 mg

List Price:

$638.00

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