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Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with *ALDH6A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of ALDH6A1 using rabbit polyclonal ALDH6A1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH6A1 gene (Lane 2).
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with *ALDH6A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

ALDH6A1 Antibody

CATALOG NUMBER: 57-923

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This ALDH6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-396 amino acids from the C-terminal region of human ALDH6A1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
58 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALDH6A1
Additional Names:
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating], Aldehyde dehydrogenase family 6 member A1, ALDH6A1, MMSDH
Protein Accession Number:
Q02252
Protein Gi Number:
12643424
Ncbi Gene Id Number:
4329
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Background Reference 1:
Kuiper,H., Cytogenet. Genome Res. 109 (4), 533 (2005)
Background Reference 2:
Anderson,N.L., Mol. Cell Proteomics(4), 311-326 (2004)
Background Reference 3:
Chambliss,K.L., J. Inherit. Metab. Dis. 23 (5), 497-504 (2000)
Background Reference 4:
Kedishvili,N.Y., J. Biol. Chem. 267 (27), 19724-19729 (1992)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-923

List Size:
400 ul

List Price:

$495.00

Datasheet
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