ALG11 Antibody

CATALOG NUMBER: 59-672

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-468 amino acids from the C-terminal region of human ALG11.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALG11
Additional Names:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase, ALG11, GT8
Protein Accession Number:
Q2TAA5
Protein Gi Number:
156631015
Ncbi Gene Id Number:
440138
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes aGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase whichis localized to the cytosolic side of the endoplasmic reticulum(ER) and catalyzes the transfer of the fourth and fifth mannoseresidue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol andMan4GlcNAc2-PP-dolichol resulting in the production ofMan5GlcNAc2-PP-dolichol. Mutations in this gene are associated withcongenital disorder of glycosylation type Ip (CDGIP). This geneoverlaps but is distinct from the UTP14, U3 small nucleolarribonucleoprotein, homolog C (yeast) gene. A pseudogene of theGDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase hasbeen identified on chromosome 19.
Background Reference 1:
Rind, N., et al. Hum. Mol. Genet. 19(8):1413-1424(2010)
Background Reference 2:
Rohozinski, J., et al. Biol. Reprod. 74(4):644-651(2006)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-672

List Size:
400 ul

List Price:

$495.00

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