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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

ALG2 Antibody

CATALOG NUMBER: 59-049

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ALG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of human ALG2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALG2
Additional Names:
Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2 homolog, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, ALG2
Protein Accession Number:
Q9H553
Protein Gi Number:
46395991
Ncbi Gene Id Number:
85365
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the glycosyltransferase 1family. The encoded protein acts as an alpha 1,3mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolicholdiphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to formMan(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene havebeen associated with congenital disorder of glycosylation type Ih(CDG-Ii). Alternative splicing results in multiple transcriptvariants.
Background Reference 1:
Inuzuka, T., et al. BMC Struct. Biol. 10, 25 (2010) :
Background Reference 2:
Okumura, M., et al. Biochem. Biophys. Res. Commun. 386(1):237-241(2009)
Background Reference 3:
Hoj, B.R., et al. Biochem. Biophys. Res. Commun. 378(1):145-148(2009)
Background Reference 4:
Mahul-Mellier, A.L., et al. J. Biol. Chem. 283(50):34954-34965(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-049

List Size:
400 ul

List Price:

$495.00

Datasheet
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