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Western blot analysis of anti-ALOX5AP Antibody in K562 cell line lysates (35ug/lane).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of anti-ALOX5AP Antibody in K562 cell line lysates (35ug/lane).

ALOX5AP Antibody

CATALOG NUMBER: 63-277

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rabbit, Rat
Immunogen:
This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALOX5AP
Additional Names:
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP, FLAP
Protein Accession Number:
P20292
Protein Gi Number:
120267
Ncbi Gene Id Number:
241
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Background Reference 1:
Zintzaras,E., Am. J. Epidemiol. 169 (5), 523-532 (2009)
Background Reference 2:
Crosslin,D.R., Hum. Genet. 125 (2), 217-229 (2009)
Background Reference 3:
Steinhilber,D., Pharm Acta Helv 69 (1), 3-14 (1994)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-277

List Size:
400 ul

List Price:

$495.00

Datasheet
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