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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Western blot analysis in mouse kidney tissue lysates (35ug/lane).

ALOXE3 Antibody

CATALOG NUMBER: 55-184

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This ALOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human ALOXE3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
81 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ALOXE3
Additional Names:
Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy icosatetraenoate dehydratase, ALOXE3
Protein Accession Number:
Q9BYJ1
Protein Gi Number:
27923803
Ncbi Gene Id Number:
59344
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ALOXE3 is a member of the lipoxygenase family, whichare catabolized by arachidonic acid-derived compounds. The encodedenzyme is a hydroperoxide isomerase that synthesizes a unique typeof epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoicacid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). Thisepoxy alcohol can activate the the nuclear receptor peroxisomeproliferator-activated receptor alpha (PPARalpha), which isimplicated in epidermal differentiation. Loss of function of theenzyme encoded by this gene results in ichthyosis, implicating thefunction of this gene in the differentiation of human skin.
Background Reference 1:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 2:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Background Reference 3:
Vahlquist, A., et al. J. Invest. Dermatol. 130(2):438-443(2010)
Background Reference 4:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-184

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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