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Western blot testing of human samples with Als2Cr2 antibody at 6ug/ml.
Western blot testing of human samples with Als2Cr2 antibody at 6ug/ml.

Als2Cr2 Antibody

CATALOG NUMBER: 33-008

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western blot: 5-10 ug/ml
Provided assay concentrations are suggestions only, Als2Cr2 antibody titration may be required for optimal results. This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms.
Purification:
Protein A affinity chromatography
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration:
0.5 mg/mL
Storage Conditions:
Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Ncbi Official Symbol:
STRADB
Additional Names:
ILPIP Antibody: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta
Ncbi Gene Id Number:
55437
User Note:
Optimal dilutions for each application to be determined by the researcher
Background:
Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

33-008

List Size:
100 ug

List Price:

$520.00

Datasheet
Shipping Info

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