AMFR Antibody

CATALOG NUMBER: 58-127

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the Central region of human AMFR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
73 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AMFR
Additional Names:
E3 ubiquitin-protein ligase AMFR, 632-, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, gp78, AMFR, RNF45
Protein Accession Number:
Q9UKV5
Protein Gi Number:
34922250
Ncbi Gene Id Number:
267
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Autocrine motility factor is a tumor motility-stimulatingprotein secreted by tumor cells. The protein encoded by this geneis a glycosylated transmembrane protein and a receptor forautocrine motility factor. The receptor, which shows some sequencesimilarity to tumor protein p53, is localized to the leading andtrailing edges of carcinoma cells.
Background Reference 1:
Joshi, B., et al. J. Biol. Chem. 285(12):8830-8839(2010)
Background Reference 2:
Bernardi, K.M., et al. Mol. Biol. Cell 21(1):140-151(2010)
Background Reference 3:
Ballar, P., et al. Int. J. Biochem. Cell Biol. 42(1):167-173(2010)
Background Reference 4:
Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390(3):758-762(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-127

List Size:
400 ul

List Price:

$495.00

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