AMOT Antibody

CATALOG NUMBER: 60-019

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AMOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-267 amino acids from the N-terminal region of human AMOT.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
118 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AMOT
Additional Names:
Angiomotin, AMOT, KIAA1071
Protein Accession Number:
Q4VCS5
Protein Gi Number:
74753814
Ncbi Gene Id Number:
154796
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene belongs to the motin family of angiostatinbinding proteins characterized by conserved coiled-coil domains andC-terminal PDZ binding motifs. The encoded protein is expressedpredominantly in endothelial cells of capillaries as well as largervessels of the placenta where it may mediate the inhibitory effectof angiostatin on tube formation and the migration of endothelialcells toward growth factors during the formation of new bloodvessels. Alternative splicing results in multiple transcriptvariants encoding different isoforms.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Heller, B., et al. J. Biol. Chem. 285(16):12308-12320(2010)
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Gagne, V., et al. Cell Motil. Cytoskeleton 66(9):754-768(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-019

List Size:
400 ul

List Price:

$495.00

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