ANGPTL7 Recombinant Protein

CATALOG NUMBER: 96-822

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 27 - Pro 346
Fusion Tag:
His Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
39 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human ANGPTL7, His Tag at 5 ug/mL (100 uL/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 ug/mL (Routinely tested).
Purity:
>85% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
ANGPTL7
Additional Names:
ANGPTL7,CDT6
Protein Accession Number:
O43827-1
Ncbi Gene Id Number:
10218
Background:
Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Background Reference 1:
Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788.
Background Reference 2:
Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693.
Background Reference 3:
Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-822

List Size:
0.1 mg

List Price:

$627.00

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