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Western blot analysis of APPL2 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate.
Western blot analysis of APPL2 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in NCI-H292 cell line lysate.

APPL2 Antibody

CATALOG NUMBER: 59-215

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This APPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human APPL2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
APPL2
Additional Names:
DCC-interacting protein 13-beta, Dip13-beta, Adapter protein containing PH domain, PTB domain and leucine zipper motif 2, APPL2, DIP13B
Protein Accession Number:
Q8NEU8
Protein Gi Number:
160419148
Ncbi Gene Id Number:
55198
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
Background Reference 1:
Chial, H.J., et al. PLoS ONE(8), E12471 (2010) :
Background Reference 2:
Rashid, S., et al. J. Biol. Chem. 284(27):18115-18128(2009)
Background Reference 3:
Chial, H.J., et al. Traffic 9(2):215-229(2008)
Background Reference 4:
Nechamen, C.A., et al. Mol. Cell. Endocrinol. 260-262, 93-99 (2007) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-215

List Size:
400 ul

List Price:

$495.00

Datasheet
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