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Western Blot at 1:4000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
ARHB Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western Blot at 1:4000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.

ARHB Antibody

CATALOG NUMBER: 56-309

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:4000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RHOB
Additional Names:
Rho-related GTP-binding protein RhoB, Rho cDNA clone 6, h6, RHOB, ARH6, ARHB
Protein Accession Number:
P62745
Protein Gi Number:
51338601
Ncbi Gene Id Number:
388
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Background Reference 1:
Adly, M.A., et al. J. Cutan. Pathol. 37(7):751-757(2010)
Background Reference 2:
Connolly, E.C., et al. Mol. Cancer Res. 8(5):691-700(2010)
Background Reference 3:
Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
Background Reference 4:
Kim, C.H., et al. Biochem. Biophys. Res. Commun. 391(2):1182-1186(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-309

List Size:
400 ul

List Price:

$495.00

Datasheet
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