ARHGEF1 Antibody

CATALOG NUMBER: 58-055

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARHGEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the N-terminal region of human ARHGEF1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
102 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF1
Additional Names:
Rho guanine nucleotide exchange factor 1, 115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub15, ARHGEF1
Protein Accession Number:
Q92888
Protein Gi Number:
34395524
Ncbi Gene Id Number:
9138
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein may formcomplex with G proteins and stimulate Rho-dependent signals.Multiple alternatively spliced transcript variants have been foundfor this gene, but the full-length nature of some variants has notbeen defined.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Loirand, G., et al. Med Sci (Paris) 26 (6-7), 561-563 (2010) :
Background Reference 3:
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-055

List Size:
400 ul

List Price:

$495.00

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