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Western blot analysis in 293 cell line lysates (35ug/lane).
Western blot analysis in 293 cell line lysates (35ug/lane).

ARHGEF18 Antibody

CATALOG NUMBER: 59-511

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARHGEF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human ARHGEF18.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
131 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF18
Additional Names:
Rho guanine nucleotide exchange factor 18, 114 kDa Rho-specific guanine nucleotide exchange factor, p114-Rho-GEF, p114RhoGEF, Septin-associated RhoGEF, SA-RhoGEF, ARHGEF18, KIAA0521
Protein Accession Number:
Q6ZSZ5
Protein Gi Number:
296439444
Ncbi Gene Id Number:
23370
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rho GTPases are GTP binding proteins that regulate a widespectrum of cellular functions. These cellular processes includecytoskeletal rearrangements, gene transcription, cell growth andmotility. Activation of Rho GTPases is under the direct control ofguanine nucleotide exchange factors (GEFs). The protein encoded bythis gene is a guanine nucleotide exchange factor and belongs tothe Rho GTPase GFE family. Family members share a common feature, aDbl (DH) homology domain followed by a pleckstrin (PH) homologydomain. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Background Reference 1:
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
Background Reference 2:
Niu, J., et al. Circ. Res. 93(9):848-856(2003)
Background Reference 3:
Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
Background Reference 4:
Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-511

List Size:
400 ul

List Price:

$495.00

Datasheet
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