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Western blot analysis in human placenta tissue lysates (35ug/lane).
Western blot analysis in human placenta tissue lysates (35ug/lane).

ARHGEF4 Antibody

CATALOG NUMBER: 60-045

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARHGEF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 573-599 amino acids from the C-terminal region of human ARHGEF4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
79 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF4
Additional Names:
Rho guanine nucleotide exchange factor 4, APC-stimulated guanine nucleotide exchange factor 1, Asef, Asef1, ARHGEF4, KIAA1112
Protein Accession Number:
Q9NR80
Protein Gi Number:
229463003
Ncbi Gene Id Number:
1.0193E+13
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein may formcomplex with G proteins and stimulate Rho-dependent signals. Thisprotein is similar to rat collybistin protein. Alternative splicingof this gene generates two transcript variants which encodedifferent isoforms. Also there is possibility for the usage ofmultiple polyadenylation sites for this gene.
Background Reference 1:
Lyons, R., et al. Leuk. Res. 34(1):109-115(2010)
Background Reference 2:
Kawasaki, Y., et al. J. Biol. Chem. 284(33):22436-22443(2009)
Background Reference 3:
Itoh, R.E., et al. J. Cell. Sci. 121 (PT 16), 2635-2642 (2008) :
Background Reference 4:
Kurzik-Dumke, U., et al. Cell. Signal. 19(9):1973-1985(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-045

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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