ARHGEF5 Antibody

CATALOG NUMBER: 58-689

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARHGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1503-1530 amino acids from the C-terminal region of human ARHGEF5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
177 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF5
Additional Names:
Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIM, ARHGEF5, TIM
Protein Accession Number:
Q12774
Protein Gi Number:
290457679
Ncbi Gene Id Number:
7984
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rho GTPases play a fundamental role in numerous cellularprocesses initiated by extracellular stimuli that work through Gprotein coupled receptors. The encoded protein may form a complexwith G proteins and stimulate Rho-dependent signals. This proteinmay be involved in the control of cytoskeletal organization.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Wang, Z., et al. J. Biol. Chem. 284(42):28599-28606(2009)
Background Reference 4:
Lin, Y.M., et al. Mol. Carcinog. 47(12):925-933(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-689

List Size:
400 ul

List Price:

$495.00

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