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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

ARHGEF6 Antibody

CATALOG NUMBER: 58-685

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
87 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ARHGEF6
Additional Names:
Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
Protein Accession Number:
Q15052
Protein Gi Number:
17371603
Ncbi Gene Id Number:
9459
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein belongs toa family of cytoplasmic proteins that activate the Ras-like familyof Rho proteins by exchanging bound GDP for GTP. It may form acomplex with G proteins and stimulate Rho-dependent signals. Thisprotein is activated by PI3-kinase. Mutations in this gene cancause X-chromosomal non-specific mental retardation. [provided byRefSeq].
Background Reference 1:
Maiti, A.K. Pharmacogenomics J. 10(2):94-104(2010)
Background Reference 2:
Eriguchi, M., et al. J. Neurol. Sci. 290 (1-2), 80-85 (2010) :
Background Reference 3:
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Background Reference 4:
Lim, J.W., et al. Scand. J. Gastroenterol. 44(10):1166-1172(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-685

List Size:
400 ul

List Price:

$495.00

Datasheet
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