ASB2 Antibody

CATALOG NUMBER: 59-067

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ASB2
Additional Names:
Ankyrin repeat and SOCS box protein 2, ASB-2, ASB2
Protein Accession Number:
Q96Q27
Protein Gi Number:
20531999
Ncbi Gene Id Number:
51676
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of theankyrin repeat and SOCS box-containing (ASB) family of proteins.They contain ankyrin repeat sequence and SOCS box domain. The SOCSbox serves to couple suppressor of cytokine signalling (SOCS)proteins and their binding partners with the elongin B and Ccomplex, possibly targeting them for degradation. This gene isinduced by all-trans retinoic acid. In myeloid leukemia cells, theexpression of this encoded protein has been shown to induce growthinhibition and chromatin condensation. Multiple alternativelyspliced transcript variants have been described for this gene buttheir full length sequences are not known.
Background Reference 1:
Heuze, M.L., et al. Blood 112(13):5130-5140(2008)
Background Reference 2:
Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005)
Background Reference 3:
Heuze, M.L., et al. J. Biol. Chem. 280(7):5468-5474(2005)
Background Reference 4:
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-067

List Size:
400 ul

List Price:

$495.00

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