ASH2L Antibody

CATALOG NUMBER: 79-687

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
ASH2L antibody was raised against a peptide sequence around aa.620~624 (G-R-R-S-P) derived from Human ASH2L.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total ASH2L protein.
Predicted Molecular Weight:
65, 80 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ASH2L
Additional Names:
ASH2, Bre2, ASH2L1, ASH2L2, ASH2
Protein Accession Number:
NP_004665.2
Protein Gi Number:
157412280
Ncbi Gene Id Number:
9070
Background:
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Background Reference 1:
Wysocka J., Myers M. P., Laherty C. D., Eisenman R. N., Herr W. Genes Dev. 17:896-911 (2003) Patel A., Dharmarajan V., Vought V. E., Cosgrove M. S. J. Biol. Chem. 284:24242-24256 (2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-687

List Size:
0.1 mg

List Price:

$370.00

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