ATP1A3 Antibody

CATALOG NUMBER: 60-827

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen:
This ATP1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-833 amino acids from the Central region of human ATP1A3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
112 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ATP1A3
Additional Names:
Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3, ATP1A3
Protein Accession Number:
P13637
Protein Gi Number:
116241260
Ncbi Gene Id Number:
478
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the family ofP-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane proteinresponsible for establishing and maintaining the electrochemicalgradients of Na and K ions across the plasma membrane. Thesegradients are essential for osmoregulation, for sodium-coupledtransport of a variety of organic and inorganic molecules, and forelectrical excitability of nerve and muscle. This enzyme iscomposed of two subunits, a large catalytic subunit (alpha) and asmaller glycoprotein subunit (beta). The catalytic subunit ofNa+/K+ -ATPase is encoded by multiple genes. This gene encodes analpha 3 subunit.
Background Reference 1:
Einholm, A.P., et al. J. Biol. Chem. 285(34):26245-26254(2010)
Background Reference 2:
Floyd, R.V., et al. Reprod Sci 17(4):366-376(2010)
Background Reference 3:
Hauck, C., et al. Eur. J. Pharmacol. 622 (1-3), 7-14 (2009) :
Background Reference 4:
Blanco-Arias, P., et al. Hum. Mol. Genet. 18(13):2370-2377(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-827

List Size:
400 ul

List Price:

$495.00

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