ATP2A2 Antibody

CATALOG NUMBER: 58-877

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
115 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ATP2A2
Additional Names:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
Protein Accession Number:
P16615
Protein Gi Number:
114312
Ncbi Gene Id Number:
488
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, whichare intracellular pumps located in the sarcoplasmic or endoplasmicreticula of muscle cells. This enzyme catalyzes the hydrolysis ofATP coupled with the translocation of calcium from the cytosol intothe sarcoplasmic reticulum lumen, and is involved in regulation ofthe contraction/relaxation cycle. Mutations in this gene causeDarier-White disease, also known as keratosis follicularis, anautosomal dominant skin disorder characterized by loss of adhesionbetween epidermal cells and abnormal keratinization. Alternativesplicing results in multiple transcript variants encoding differentisoforms.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Tuusa, J.T., et al. FEBS J. 277(13):2815-2829(2010)
Background Reference 3:
Godic, A., et al. EurDermatol 20(3):271-275(2010)
Background Reference 4:
Godic, A., et al. J. Am. Acad. Dermatol. 62(5):819-823(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-877

List Size:
400 ul

List Price:

$495.00

Shipping Info
Customize your order
Custom Antibody Services

New & Featured Products

CATALOG NUMBER: PM-7369-HRP

CATALOG NUMBER: PM-7369-biotin

CATALOG NUMBER: PM-7369