ATPase (phospho Ser16) Antibody

CATALOG NUMBER: 79-988

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
ATPase (phospho Ser16) antibody was raised against a peptide sequence around phosphorylation site of serine 16 (A-V-S (p)-E-Q) derived from Human ATPase.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of ATPase only when phosphorylated at serine 16.
Predicted Molecular Weight:
112 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
ATP1A1
Additional Names:
A1A1, AT1A1, ATP1A1, K-ATPase 1, Sodium pump 1
Protein Accession Number:
NP_000692.2
Protein Gi Number:
114374
Ncbi Gene Id Number:
476
Background:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Background Reference 1:
Kava L, Rossi NF, Mattingly R, Yingst DR (2012) Am J Hypertens 25, 487-91
Background Reference 2:
Soltoff SP, Asara JM, Hedden L (2010)J Biol Chem 285, 36330-8
Background Reference 3:
Efendiev R, et al. (2006) FEBS Lett 580, 5067-70

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-988

List Size:
0.1 mg

List Price:

$376.00

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