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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

AUP1 Antibody

CATALOG NUMBER: 58-566

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AUP1
Additional Names:
Ancient ubiquitous protein 1, AUP1
Protein Accession Number:
Q9Y679
Protein Gi Number:
12643958
Ncbi Gene Id Number:
550
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that contains a domain withhomology to the ancient conserved region of the archain 1 gene anda domain that may be involved in binding ubiquitin-conjugatingenzymes. The protein encoded by this gene has been shown to bind tothe conserved membrane-proximal sequence of the cytoplasmic tail ofintegrin alpha(IIb) subunits. These subunits play a crucial role inthe integrin alpha(IIb)beta(3) inside-out signalling in plateletsand megakaryocytes that leads to platelet aggregation and thrombusformation. This gene overlaps the gene for mitochondrial serineprotease 25.
Background Reference 1:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 2:
Kato, A., et al. J. Biol. Chem. 277(32):28934-28941(2002)
Background Reference 3:
Karpisheva, K.V., et al. Tsitologiia 44(9):846-851(2002)
Background Reference 4:
Karpisheva, K.V., et al. Tsitologiia 44(9):839-845(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-566

List Size:
400 ul

List Price:

$495.00

Datasheet
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