AVPR1B Antibody

CATALOG NUMBER: 57-446

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AVPR1B
Additional Names:
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
Protein Accession Number:
P47901
Protein Gi Number:
1351392
Ncbi Gene Id Number:
553
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene acts as receptor forarginine vasopressin. This receptor belongs to the subfamily ofG-protein coupled receptors which includes AVPR1A, V2R and OXTreceptors. Its activity is mediated by G proteins which stimulate aphosphatidylinositol-calcium second messenger system. The receptoris primarily located in the anterior pituitary, where it stimulatesACTH release. It is expressed at high levels in ACTH-secretingpituitary adenomas as well as in bronchial carcinoids responsiblefor the ectopic ACTH syndrome. A spliced antisense transcript ofthis gene has been reported but its function is not known.
Background Reference 1:
van West, D., et al. Psychiatry Res 179(1):64-68(2010)
Background Reference 2:
Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)
Background Reference 3:
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Background Reference 4:
van West, D., et al. Psychiatr. Genet. 19(2):102-103(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-446

List Size:
400 ul

List Price:

$495.00

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