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Western blot analysis in WiDr cell line lysates (35ug/lane).
Western blot analysis of AZU1 using rabbit polyclonal AZU1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AZU1 gene.
Western blot analysis in WiDr cell line lysates (35ug/lane).

AZU1 Antibody

CATALOG NUMBER: 58-140

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This AZU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human AZU1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
27 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
AZU1
Additional Names:
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1
Protein Accession Number:
P20160
Protein Gi Number:
416746
Ncbi Gene Id Number:
566
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Azurophil granules, specialized lysosomes of theneutrophil, contain at least 10 proteins implicated in the killingof microorganisms. The protein encoded by this gene is an azurophilgranule antibiotic protein, with monocyte chemotactic andantibacterial activity. It is also an important multifunctionalinflammatory mediator. This encoded protein is a member of theserine protease gene family but it is not a serine proteinase,because the active site serine and histidine residues are replaced.The genes encoding this protein, neutrophil elastase 2, andproteinase 3 are in a cluster located at chromosome 19pter. All 3genes are expressed coordinately and their protein products arepackaged together into azurophil granules during neutrophildifferentiation.
Background Reference 1:
Changho, S., et al. Pathol. Res. Pract. 206(5):314-317(2010)
Background Reference 2:
Linder, A., et al. J. Invest. Dermatol. 130(5):1365-1372(2010)
Background Reference 3:
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Background Reference 4:
Wilker, E., et al. Environ. Health Perspect. 117(6):935-940(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-140

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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