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The purity of rh AZU1 / HBP was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
The purity of rh AZU1 / HBP was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Azurocidin Recombinant Protein

CATALOG NUMBER: 96-038

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ile 27 - Pro 250
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
25 kDa
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
AZU1
Additional Names:
AZU1, Azurocidin, HBP, AZAMP, AZU, CAP37, HUMAZUR, NAZC
Protein Accession Number:
AAH69495
Ncbi Gene Id Number:
566
Background:
Azurocidin (AZU1) is also known as Heparin-binding protein (HBP), Cationic antimicrobial protein CAP37, is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. which belongs to the peptidase S1 family and elastase subfamily. AZU1 / HBP contains 1 peptidase S1 domain. AZU1 binds heparin. The cytotoxic action of AZU1 is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. AZU1 may play a role in mediating recruitment of monocytes in the second wave of inflammation.
Background Reference 1:
Wasiluk K.R., et al., 1991, Infect. Immun. 59:4193-4200.
Background Reference 2:
Miyasaki K.T., 1992, Infect. Immun. 60:4973-4975.
Background Reference 3:
Linder A., 2009, Clin. Infect. Dis. 49 (7): 1044–50.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-038

List Size:
0.1 mg

List Price:

$495.00

Datasheet
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