B-RAF (phospho Thr599) Antibody

CATALOG NUMBER: 79-804

Clonality:
Polyclonal
Tested Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
B-RAF (phospho Thr599) antibody was raised against a peptide sequence around phosphorylation site of threonine 599 (L-A-T (p)-V-K) derived from Human B-RAF.
Conjugate:
Unconjugated
Tested Applications:
IHC
Specificity:
The antibody detects endogenous levels of B-Raf only when phosphorylated at threonine 598.
Predicted Molecular Weight:
84 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
BRAF
Additional Names:
B-RAF, RAFB1, RMIL, BRAF1, c-RMIL
Protein Accession Number:
NP_004324.2
Protein Gi Number:
50403720
Ncbi Gene Id Number:
673
Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
Background Reference 1:
Armelle Calipel, J. Biol. Chem., Oct 2003; 278: 42409 - 42418.
Background Reference 2:
Tara J. Dillon, J. Biol. Chem., Sep 2003; 278: 35940 - 35949.
Background Reference 3:
R K Jaiswal, Mol. Cell. Biol., Oct 1994; 14: 6944 - 6953.
Background Reference 4:
Laura L. Dugan, J. Biol. Chem., Sep 1999; 274: 25842.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-804

List Size:
0.1 mg

List Price:

$376.00

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