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BAFF and Receptor Detection Set

CATALOG NUMBER: PSI-1803

Clonality:
Polyclonal
Tested Applications:
IF, IHC, WB
Species Reactivity:
Human
Specifications
Species Reactivity:
Human
Immunogen:
Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
Tested Applications:
IF, IHC, WB
Set Contents:
BAFF Antibody, Cat. No. 2221 (50 μg)

APRIL Antibody, Cat. No. 2415 (50 μg)

TACI Antibody, Cat. No. 2395 (50 μg)

BCMA Antibody, Cat. No. 2397 (50 μg)

BAFF-R Antibody, Cat. No. 3097 (50 μg)
Purification:
Antibodies are supplied as affinity chromatography purified IgG.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
PBS containing 0.02% sodium azide.
Concentration:
Antibody 1 mg/mL
Storage Conditions:
Stable at 4°C for three months, store at -20°C for up to one year.
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL; a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.

For images please see PDF data sheet
Background Reference 1:
Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. >Science 1999; 285:260-3.
Background Reference 2:
Schneider P, MacKay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999; 189:1747-56.
Background Reference 3:
Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leuk Biol 1999; 65:680-3.
Background Reference 4:
Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med. 1998; 188(6):1185-90.
Set Contents:
BAFF Antibody, Cat. No. 2221 (50 μg)

APRIL Antibody, Cat. No. 2415 (50 μg)

TACI Antibody, Cat. No. 2395 (50 μg)

BCMA Antibody, Cat. No. 2397 (50 μg)

BAFF-R Antibody, Cat. No. 3097 (50 μg)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

PSI-1803

List Size:
1 Set

List Price:

$849.00

Out of stock

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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