BAFF Antibody [4.62] (biotin)

CATALOG NUMBER: 36-120

Clonality:
Monoclonal
Tested Applications:
ELISA, Functional Assays, IP
Host Species:
Rat
Species Reactivity:
Human
Conjugate:
Biotin
Specifications
Host Species:
Rat
Species Reactivity:
Human
Immunogen:
HA-tagged human BAFF.
Conjugate:
Biotin
Tested Applications:
ELISA, Functional Assays, IP
Application Note:
ELISA: (as a detection antibody). Functional Application: Inhibition of human BAFF binding. Immunoprecipitation: (1:200).
Specificity:
Recognizes human BAFF.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG2a
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
0.5 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
TNFSF13B
Additional Names:
BLyS; TALL-1; CD257; B Cell Activating Factor; TNFSF13B
Protein Accession Number:
5730097
Protein Gi Number:
NP_006564
Ncbi Gene Id Number:
10673
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-120

List Size:
100 ug

List Price:

$577.00

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