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Immobilized Human BAFF, His Tag at 5 ug/mL (100 uL/well) can bind Mouse BAFFR, Fc Tag with a linear range of 0.3-13 ng/mL.
Immobilized Human BAFF, His Tag at 5 ug/mL (100 uL/well) can bind Mouse BAFFR, Fc Tag with a linear range of 0.3-13 ng/mL.

BAFFR Recombinant Protein

CATALOG NUMBER: 96-976

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Ser 10 - Ala 71
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
33.3 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human BAFF, His Tag at 5 ug/mL (100 uL/well) can bind Mouse BAFFR, Fc Tag with a linear range of 0.3-13 ng/mL.
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
BAFFR
Additional Names:
BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin
Protein Accession Number:
NP_082351.1
Ncbi Gene Id Number:
72049
Background:
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Background Reference 1:
Thompson JS., et al.,2001, Science, 293 (5537): 2108-2111.
Background Reference 2:
Mbrose CM., 2003, Journal of Biological Regulators and Homeostatic Agents, 16 (3): 211-213.
Background Reference 3:
Treml LS., et al., 2006, Seminars in Immunology, 18 (5): 297-304.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-976

List Size:
0.1 mg

List Price:

$540.00

Datasheet
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