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Antibody used in IHC on Human Lung.
Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Antibody used in IHC on Human Lung.

BCHE Antibody

CATALOG NUMBER: 29-965

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCHE.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
BCHE antibody can be used for detection of BCHE by ELISA at 1:312500. BCHE antibody can be used for detection of BCHE by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
68 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store BCHE antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
BCHE
Additional Names:
BCHE, CHE1, E1, CHE2
Protein Accession Number:
NP_000046
Protein Gi Number:
4557351
Ncbi Gene Id Number:
590
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Background Reference 1:
Gao, D. (2006) Proteins 62 (1), 99-110.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

29-965

List Size:
100 ul

List Price:

$473.00

Datasheet
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