Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis using BCL10 monoclonal antibody against truncated BCL10 recombinant protein and MCF - 7 cell lysate.
Immunohistochemical analysis of paraffin - embedded liver carcinoma showing cytoplasmic localization using BCL10 antibody with DAB staining.
Western blot analysis using BCL10 monoclonal antibody against truncated BCL10 recombinant protein and MCF - 7 cell lysate.

BCL10 Antibody [4F8E8H8]

CATALOG NUMBER: 32-115

Clonality:
Monoclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Mouse
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Mouse
Species Reactivity:
Human
Immunogen:
Ni-NTA purified recombinant human BCL-10 expressed in E. Coli strain BL21 (DE3).
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
IHC(P):Dilution 1:1,000 - 1:2,000
IHC(F):Dilution 1:1,000 - 1:2,000
Western blot:Dilution 1:2,000 - 1:5,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Purification:
Antibody is purified by protein A affinity chromatography.
Clonality:
Monoclonal
Isotype:
IgG1
physical-state:
Liquid
Concentration:
batch dependent
Storage Conditions:
BCL-10 monoclonal antibody can be stored at -20°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BCL10
Additional Names:
CIPER, CLAP, CARD-containing molecule enhancing NF-kappa-B, Bcl-10, mE10, CIPER, c-E10, CARMEN
Protein Accession Number:
O95999
Protein Gi Number:
20454813
Ncbi Gene Id Number:
8915
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
B-cell CLL/lymphoma 10, also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-κB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-κB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-κB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Background Reference 1:
Willis, T.G., et al. (1999) Cell. 96, 35-45.
Background Reference 2:
Lucas, P.C., et al. (2001) J. Biol.Chem. 276, 19012-19019.
Background Reference 3:
Wang, L., et al. (2001) J. Biol.Chem. 276, 21405-21409

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

32-115

List Size:
0.1 mg

List Price:

$408.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369