BEAN Antibody

CATALOG NUMBER: 57-024

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
29 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BEAN1
Additional Names:
Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN, BEAN1
Protein Accession Number:
Q3B7T3
Protein Gi Number:
190360694
Ncbi Gene Id Number:
146227
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is one of severalproteins that interact with NEDD4, a member of a family ofubiquitin-protein ligases. These proteins have PY motifs in commonthat bind to the WW domains of NEDD4. NEDD4 is developmentallyregulated, and is highly expressed in embryonic tissues. Mutationsin this gene (i.e., intronic insertions of >100 copies ofpentanucleotide repeats including a (TGGAA)n sequence) areassociated with spinocerebellar ataxia type 31. Alternativelyspliced transcript variants encoding different isoforms have beenfound for this gene.
Background Reference 1:
Sato, N., et al. Am. J. Hum. Genet. 85(5):544-557(2009)
Background Reference 2:
Jolliffe, C.N., et al. Biochem. J. 351 PT 3, 557-565 (2000) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-024

List Size:
400 ul

List Price:

$495.00

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