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Western blot analysis in T47D cell line lysates (35ug/lane).
Western blot analysis in T47D cell line lysates (35ug/lane).

BEST3 Antibody

CATALOG NUMBER: 60-376

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
76 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BEST3
Additional Names:
Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3
Protein Accession Number:
Q8N1M1
Protein Gi Number:
38503351
Ncbi Gene Id Number:
144453
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
BEST3 belongs to the bestrophin family of anion channels,which includes BEST1 (MIM 607854), the gene mutant in vitelliformmacular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins aretransmembrane (TM) proteins that share a homology region containinga high content of aromatic residues, including an invariantarg-phe-pro (RFP) motif. The bestrophin genes share a conservedgene structure, with almost identical sizes of the 8 RFP-TMdomain-encoding exons and highly conserved exon-intron boundaries.Each of the 4 bestrophin genes has a unique 3-prime end of variablelength (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al.,2003 [PubMed 12907679]).
Background Reference 1:
Marsey, L.L., et al. J. Physiol. (Lond.) 587 (PT 10), 2211-2224 (2009) :
Background Reference 2:
Qu, Z.Q., et al. J. Biol. Chem. 282(24):17460-17467(2007)
Background Reference 3:
Tsunenari, T., et al. J. Biol. Chem. 278(42):41114-41125(2003)
Background Reference 4:
Stohr, H., et al. Eur. J. Hum. Genet. 10(4):281-284(2002)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-376

List Size:
400 ul

List Price:

$495.00

Datasheet
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