beta-Defensin 1 Recombinant Protein

CATALOG NUMBER: 91-108

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Gly22-Lys68
Fusion Tag:
Tag Free
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Predicted Molecular Weight:
5.07 kD
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
physical-state:
Lyophilized
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Storage Conditions:
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at -20°C for 3 months.
Ncbi Official Symbol:
DEFB1
Additional Names:
Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1
Protein Accession Number:
P60022
Ncbi Gene Id Number:
1672
Background:
beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

91-108

List Size:
0.05 mg

List Price:

$515.00

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