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Bmf Antibody [17A9]

CATALOG NUMBER: 36-174

Clonality:
Monoclonal
Tested Applications:
ELISA, Flow, ICC, IHC, IP, WB
Host Species:
Rat
Species Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Mouse, Rat
Immunogen:
Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.
Conjugate:
Unconjugated
Tested Applications:
ELISA, Flow, ICC, IHC, IP, WB
Application Note:
Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).
Specificity:
Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25kDa and ~30kDa by Western blot, corresponding to endogenous Bmf and BmfL. Does not cross-react with human Bmf.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG2a, kappa
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
Bmf
Additional Names:
Bcl-2-modifying Factor
Protein Accession Number:
56748562
Protein Gi Number:
Q91ZE9
Ncbi Gene Id Number:
171543
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-174

List Size:
100 ug

List Price:

$498.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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