Bmf Antibody [9G10]

CATALOG NUMBER: 36-173

Clonality:
Monoclonal
Tested Applications:
Flow, IP, WB
Host Species:
Rat
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rat
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant mouse Bmf.
Conjugate:
Unconjugated
Tested Applications:
Flow, IP, WB
Application Note:
Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).
Specificity:
Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.
Purification:
>95% (SDS-PAGE)
Clonality:
Monoclonal
Isotype:
IgG2a, kappa
physical-state:
Liquid
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Storage Conditions:
Stable for at least 1 year after receipt when stored at -20°C.
Ncbi Official Symbol:
BMF
Additional Names:
Bcl-2-modifying Factor
Protein Accession Number:
15723378
Protein Gi Number:
NP_277038
Ncbi Gene Id Number:
90427
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

36-173

List Size:
100 ug

List Price:

$498.00

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