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BMP-4 Recombinant Protein

CATALOG NUMBER: 40-203

Specifications
source-species:
HeLa cells
Species:
Human
source-species:
HeLa cells
Recombinant Protein Sequence:
HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Biological Activity:
Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml.
Purity:
Greater than 97% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized BMP-4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing BMP-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
BMP4
Additional Names:
ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4
Protein Accession Number:
NP_001193.2
Protein Gi Number:
157276593
Ncbi Gene Id Number:
652
Background:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-203

List Size:
0.001 mg, 0.005 mg

List Price:

Price range: $199.00 through $305.00

Datasheet
Shipping Info

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