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Antibody is used in Western blot to detect Bmp6 in HL60 cell lysate.
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp6 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Antibody is used in Western blot to detect Bmp6 in HL60 cell lysate.

Bmp6 Antibody

CATALOG NUMBER: 59-003

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This Bmp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human Bmp6.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
BMP6
Additional Names:
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1, BMP6, VGR
Protein Accession Number:
P22004
Protein Gi Number:
115076
Ncbi Gene Id Number:
654
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
Background Reference 1:
Lories, R.J., et al., Arthritis Rheum. 48(10):2807-2818 (2003).
Background Reference 2:
Bobacz, K., et al., Arthritis Rheum. 48(9):2501-2508 (2003).
Background Reference 3:
Tamada, H., et al., Biochim. Biophys. Acta 1395(3):247-251 (1998).
Background Reference 4:
Rickard, D.J., et al., J. Clin. Invest. 101(2):413-422 (1998).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-003

List Size:
400 ul

List Price:

$495.00

Datasheet
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